API5 Polyclonal Antibody (E-AB-16168)
For research use only.
Verified Samples |
Verified Samples in WB: Hela, MCF-7, A549, LoVo |
Dilution | WB 1:500-1:2000 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | WB |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human API5 |
Abbre | API5 |
Synonyms | AAC 11, AAC-11, AAC11, API 5, API-5, API5, API5 like 1, API5L1, Antiapoptosis clone 11 protein, Apoptosis inhibitor 5, Cell migration inducing gene 8 protein, Cell migration-inducing gene 8 protein, Fibroblast grow, Fibroblast growth factor 2 interacting factor 2, api5 |
Swissprot | |
Calculated MW | 59 kDa |
Cellular Localization | Cytoplasm and Nucleus. Cytoplasm. Mainly nuclear. Can also be cytoplasmic. |
Concentration | 1.1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cell Biology |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |
Other Clones
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Other Formats
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Unconjugated
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