AQP2 Polyclonal Antibody (E-AB-66725)
For research use only.
| Verified Samples |
Verified Samples in IHC: Mouse kidney Verified Samples in IF: Rat kidney, Mouse kidney |
| Dilution | IHC 1:50-1:100, IF 1:50-1:200 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human AQP2 (NP_000477.1). |
| Abbre | AQP2 |
| Synonyms | AQP-CD, AQP2, WCH-CD, WCH-CD抗体 |
| Swissprot | |
| Cellular Localization | Apical cell membrane. Basolateral cell membrane. Cytoplasmic vesicle membrane. Golgi apparatus, trans-Golgi network membrane. Shuttles from vesicles to the apical membrane. Vasopressin-regulated phosphorylation is required for translocation to the apical cell membrane. PLEKHA8/FAPP2 is required to transport AQP2 from the TGN to sites where AQP2 is phosphorylated. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20℃ Valid for 12 months. Avoid freeze/thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus. |
Note: Data for this module come from published literature that cites this product, displaying other products used together in the same research paper.
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