AR Polyclonal Antibody (E-AB-70112)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human prostate, Mouse seminal vesicle, Rat testis |
| Dilution | IHC 1:300-1:1000 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Androgen receptor |
| Abbre | AR |
| Synonyms | AIS, ANDR, AR, AR8, Androgen nuclear receptor variant 2, Androgen receptor, Androgen receptor (dihydrotestosterone receptor, DHTR, Dihydro testosterone, Kennedy disease), androgen receptor splice variant 4b, spinal and bulbar muscular atrophy, testicular feminization |
| Swissprot | |
| Cellular Localization | Cytoplasm, Nucleus. |
| Concentration | 0.83 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain.The protein functions as a steroid-hormone activated transcription factor.Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes.This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. |
Other Clones
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Other Formats
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Unconjugated
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