Arginase 1/ARG1 Polyclonal Antibody(Capture/Detector) (AN000310P)

For research use only.
Verified Samples | Verified Samples in ELISA: Recombinant Mouse Arginase 1/ARG1 protein, Mouse serum, Mouse plasma |
Dilution | ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL |
Isotype | Rabbit IgG |
Host | Rabbit |
Reactivity | Mouse |
Applications | ELISA Capture/Detector |
Clonality | Polyclonal |
Immunogen | Recombinant Mouse Arginase 1/ARG1 protein expressed by E.coli |
Abbre | Arginase 1/ARG1 |
Synonyms | Arg1, Arginase-1, Liver-type arginase, Type I arginase |
Swissprot | |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
Purification Method | Antigen Affinity Purification |
Conjugation | Unconjugated |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
background | Arginase is the focal enzyme of the urea cycle hydrolysing l-arginine to urea and l-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this enzyme in the regulation of nitric oxide (NO) synthesis and the development of vascular disease. Arginase also redirects the metabolism of l-arginine to l-ornithine and the formation of polyamines and l-proline,which are essential for smooth muscle cell growth and collagen synthesis. Arginase is encoded by two recently discovered genes (Arginase I and Arginase II). In most mammals,Arginase 1 (ARG1) also known as Arginase,liver,which functions in the urea cycle,and is located primarily in the cytoplasm of the liver. The second isozyme,Arginase II,has been implicated in the regulation of the arginine/ornithine concentrations in the cell. It is located in mitochondria of several tissues in the body,with most abundance in the kidney and prostate. It may be found at lower levels in macrophages,lactating mammary glands,and brain. |
Other Clones
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Unconjugated
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