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For research use only.

Verified Samples Verified Samples in IHC: Human colon cancer, Human breast cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human ARHGEF12
Abbre ARHGEF12
Synonyms ARHGC,  ARHGEF12,  KIAA0382,  Leukemia-associated RhoGEF,  PRO2792,  Rho guanine exchange factor (GEF) 12,  Rho guanine nucleotide exchange factor (GEF) 12,  Rho guanine nucleotide exchange factor 12,  Similar to,  leukemia-associated rho guanine nucleotide exchange factor
Swissprot
Cellular Localization Cytoplasm. Membrane. Translocated to the membrane upon stimulation.
Concentration 0.7 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Signal transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.
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Unconjugated

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