ARHGEF12 Polyclonal Antibody (E-AB-16558)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human colon cancer, Human breast cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ARHGEF12 |
| Abbre | ARHGEF12 |
| Synonyms | ARHGC, ARHGEF12, KIAA0382, Leukemia-associated RhoGEF, PRO2792, Rho guanine exchange factor (GEF) 12, Rho guanine nucleotide exchange factor (GEF) 12, Rho guanine nucleotide exchange factor 12, Similar to, leukemia-associated rho guanine nucleotide exchange factor |
| Swissprot | |
| Cellular Localization | Cytoplasm. Membrane. Translocated to the membrane upon stimulation. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. |
Other Clones
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Unconjugated
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