ARHGEF12 Polyclonal Antibody (E-AB-16558)
For research use only.
Verified Samples |
Verified Samples in IHC: Human colon cancer, Human breast cancer |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human ARHGEF12 |
Abbre | ARHGEF12 |
Synonyms | ARHGC, ARHGEF12, KIAA0382, Leukemia-associated RhoGEF, PRO2792, Rho guanine exchange factor (GEF) 12, Rho guanine nucleotide exchange factor (GEF) 12, Rho guanine nucleotide exchange factor 12, Similar to, leukemia-associated rho guanine nucleotide exchange factor |
Swissprot | |
Cellular Localization | Cytoplasm. Membrane. Translocated to the membrane upon stimulation. |
Concentration | 0.7 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Signal transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. |
Other Clones
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Other Formats
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Unconjugated
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