ARHGEF6 Polyclonal Antibody (E-AB-16170)
For research use only.
Verified Samples |
Verified Samples in IHC: Human lung cancer |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human ARHGEF6 |
Abbre | ARHGEF6 |
Synonyms | ARHG6, ARHGEF6, Alpha Pix, Alpha-Pix, COOL 2, COOL-2, COOL2, MRX46, Mental retardation, PAK interacting exchange factor alpha, PAK-interacting exchange factor alpha, PIXA, Rac/Cdc42 guanine exchange factor (GEF) 6, Rac/Cdc42 guanine nucleotide exchange fac, X linked 46 |
Swissprot | |
Cellular Localization | Cytosol, Other locations: intracellular, lamellipodium. |
Concentration | 0.7 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. |
Other Clones
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Other Formats
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Unconjugated
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