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For research use only.

Verified Samples Verified Samples in IHC: Human lung cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human ARHGEF6
Abbre ARHGEF6
Synonyms ARHG6,  ARHGEF6,  Alpha Pix,  Alpha-Pix,  COOL 2,  COOL-2,  COOL2,  MRX46,  Mental retardation,  PAK interacting exchange factor alpha,  PAK-interacting exchange factor alpha,  PIXA,  Rac/Cdc42 guanine exchange factor (GEF) 6,  Rac/Cdc42 guanine nucleotide exchange fac,  X linked 46
Swissprot
Cellular Localization Cytosol, Other locations: intracellular, lamellipodium.
Concentration 0.7 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation.
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Unconjugated

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