ARHGEF7 Polyclonal Antibody (E-AB-14609)
For research use only.
| Verified Samples |
Verified Samples in WB: Human brain malignant glioma, A172, 293T Verified Samples in IHC: Human gastric cancer, Human thyroid cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ARHGEF7 |
| Abbre | ARHGEF7 |
| Synonyms | ARHG7, ARHGEF 7, Arhgef7, Beta pix, Beta-Pix, COOL-1, COOL1, Cool, DKFZp686C12170, DKFZp761K1021, KIAA0142, KIAA0412, Nbla10314, P50, P50BP, P85COOL1, P85SPR, PAK interacting exchange factor beta, PAK-interacting exchange fac, betaPix, betaPix-b, betaPix-c, mKIAA0142, p85 |
| Swissprot | |
| Calculated MW | 90 kDa |
| Cellular Localization | Cytosol, Plasma Membrane, Other locations: cell cortex, focal adhesion, lamellipodium, neuron projection, neuronal cell body, protein complex, ruffle, storage vacuole. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Other Clones
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Other Formats
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Unconjugated
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