ARID1A Polyclonal Antibody (E-AB-12984)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human lung cancer, Human gastric cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ARID1A |
| Abbre | ARID1A |
| Synonyms | ARI1A, ARID domain containing protein 1A, ARID domain-containing protein 1A, ARID1A, AT rich interactive domain 1A, AT rich interactive domain 1A (SWI like), AT rich interactive domain containing prote, actin-dependent regulator of chromatin subfamily F member 1 |
| Swissprot | |
| Cellular Localization | Nucleus. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes.The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin.It possesses at least two conserved domains that could be important for its function.First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus.Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation.It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. |
Other Clones
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Unconjugated
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