ARIH2 Polyclonal Antibody (E-AB-12985)

Name: ARIH2 Polyclonal Antibody
Brand: Elabscience
SKU: E-AB-12985
Price: 73.0 USD
Availability: InStock

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Size	Price	Qty
200μL	$ 399.00	- +
120μL	$ 240.00	- +
60μL	$ 143.00	- +
20μL	$ 73.00	- +

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Verified Samples	Verified Samples in WB: Hela, Jurkat, 293T, K562, Mouse testis
Dilution	WB 1:500-1:2000
Isotype	Rabbit IgG
Host	Rabbit
Reactivity	Human, Mouse
Applications	WB
Clonality	Polyclonal
Immunogen	Synthetic peptide of human ARIH2
Abbre	ARIH2
Synonyms	all trans retinoic acid inducible RING finger, Ari 2, Ari-2, ARI2, Ariadne 2, Ariadne 2 protein homolog, ariadne homolog 2, ariadne homolog 2 (Drosophila), Ariadne RBR E3 ubiquitin protein ligase 2, ARIH 2, Arih2, E3 ubiq, E3 ubiquitin protein ligase ARIH2, HT005
Swissprot	O95376
Calculated MW	58 kDa
Cellular Localization	Nucleus. Cytoplasm.
Concentration	0.6 mg/mL
Buffer	Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method	Affinity purification
Research Areas	Cell Biology, Epigenetics and Nuclear Signaling
Conjugation	Unconjugated
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping	The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background	TRIAD1, also known as ARIH2 (ariadne homolog 2) or ARI2, is a 493 amino acid protein that contains one IBR-type zinc finger and two RING-type zinc fingers and belongs to the ariadne subfamily of RBR proteins. Localized to the nucleus, TRIAD1 interacts with UBE2L3 and is thought to act as an E3 ubiquitin-protein ligase, functioning to accept ubiquitin from E2 ubiquitin-conjugating enzymes and transfer the acquired ubiquitin residue to target substrates. TRIAD1 is subject to post-translational DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding TRIAD1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.

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