ASB8 Polyclonal Antibody (E-AB-10961)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human colon cancer |
| Dilution | IHC 1:25-1:100 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ASB8 |
| Abbre | ASB8 |
| Synonyms | Ankyrin repeat and SOCS box containing 8, Ankyrin repeat and SOCS box protein 8, ASB 8, ASB-8, ASB8, FLJ21255, MGC5540, OTTHUMP00000237000, OTTHUMP00000237001, OTTHUMP00000237007, OTTHUMP00000237009, OTTHUMP00000237010, PP14212 |
| Swissprot | |
| Cellular Localization | Cytoplasm. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | ASB-8 (ankyrin repeat and SOCS box-containing 8) is a 288 amino acid member of the ASB family that contains one SOCS box domain and four ANK repeats. Localized to the cytoplasm, ASB-8 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins. The highest level of ASB-8 expression has been detected in skeletal muscle. ASB-8 is also expressed in heart, brain, placenta, liver, kidney and pancreas. |
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