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For research use only.

Verified Samples Verified Samples in IHC: Human colon cancer
Dilution IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human ASB8
Abbre ASB8
Synonyms ASB 8,  ASB-8,  ASB8,  Ankyrin repeat and SOCS box containing 8,  Ankyrin repeat and SOCS box protein 8,  FLJ21255,  MGC5540,  OTTHUMP00000237000,  OTTHUMP00000237001,  OTTHUMP00000237007,  OTTHUMP00000237009,  OTTHUMP00000237010,  PP14212
Swissprot
Cellular Localization Cytoplasm.
Concentration 0.7 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background ASB-8 (ankyrin repeat and SOCS box-containing 8) is a 288 amino acid member of the ASB family that contains one SOCS box domain and four ANK repeats. Localized to the cytoplasm, ASB-8 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins. The highest level of ASB-8 expression has been detected in skeletal muscle. ASB-8 is also expressed in heart, brain, placenta, liver, kidney and pancreas.
Other Clones

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Unconjugated

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