ASH2L Polyclonal Antibody (E-AB-14753)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human colon cancer, Human liver cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ASH2L |
| Abbre | ASH2L |
| Synonyms | ASH 2, ASH2, ASH2 LIKE, ASH2 like protein, ASH2-like protein, ASH2L, ASH2L1>, ASH2L2, Ash2 (absent, Ash2 (absent small or homeotic) like, Ash2l, Bre 2, Bre2, Discs 2-like, Drosophila ASH2-like, Drosophila absent, Set, or homeotic, or homeotic) like (Drosophila), small |
| Swissprot | |
| Cellular Localization | Nucleus. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The human ASH2L gene encodes a 628 amino acid protein known as ASH2L1, or isoform 1, which contains a nuclear localization signal and PHD finger motif, suggesting that the gene product functions as a transcription regulator.Alternative splicing results in a shorter isoform 2, designated ASH2L2, which is missing the first 94 amino acid residues found in ASH2L1.Human ASH2L proteins are 60% homologous to Drosophila ash2, which positively regulates expression of certain genes in early development, and contain similar, but not identical, domains, including a zinc finger motif.ASH2L is highly expressed in fetal liver, testis and leukemia cell lines with erythroid and megakaryocytic potential, such as K562, Hel and Dami. |
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