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For research use only.

Verified Samples Verified Samples in WB: 231, Human liver cancer
Verified Samples in IHC: Human liver cancer, Human brain
Dilution WB 1:200-1:1000,  IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human ATG4A
Abbre ATG4A
Synonyms AI627006,  APG4 autophagy 4 homolog A,  ATG4 autophagy related 4 homolog A,  ATG4 autophagy related 4 homolog A (S. cerevisiae),  ATG4A,  AUT like 2 cysteine endopeptidase,  AUT-like 2 cysteine endopeptidase,  Apg4a,  Atg4al,  Autl2,  Autophag,  Autophagin 2,  Autophagin-2
Swissprot
Calculated MW 45 kDa
Cellular Localization Cytoplasm.
Concentration 0.3 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Cardiovascular,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly.Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging.Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed.This gene encodes a member of the autophagin protein family.The encoded protein is also designated as a member of the C-54 family of cysteine proteases.Transcript variants that encode distinct isoforms have been identified.
Other Clones

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Unconjugated

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