ATG4D Polyclonal Antibody (E-AB-10860)
For research use only.
Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human liver cancer |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human ATG4D |
Abbre | ATG4D |
Synonyms | 9830134P12Rik, APG4, APG4 D, APG4 autophagy 4 homolog D, APG4D, ATG4 autophagy related 4 homolog D (S. cerevisiae), ATG4D, AUT like 4 cysteine endopeptidase, AUT-like 4 cysteine endopeptidase, AUTL4, Atg4d, Atg4dl, Autophagin 4, Autophagin-4, D, S. cerevisiae, homolog of |
Swissprot | |
Cellular Localization | Cytoplasm. |
Concentration | 0.3 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. |
Other Clones
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Other Formats
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Unconjugated
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