AURKAIP1 Polyclonal Antibody (E-AB-10976)
For research use only.
| Verified Samples |
Verified Samples in WB: Human testis |
| Dilution | WB 1:500-1:2000 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human AURKAIP1 |
| Abbre | AURKAIP1 |
| Synonyms | 28S ribosomal protein S38, AIP, AKIP, AURKA interacting protein, AURKA-interacting protein, AURKAIP 1, Aurkaip1, Aurora A kinase interacting protein, Aurora kinase A interacting protein 1, Aurora kinase A-interacting protein, FLJ20608, MRP-S38, mitochondrial |
| Swissprot | |
| Calculated MW | 22 kDa |
| Cellular Localization | Mitochondrion. Nucleus. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | AKIP (AURKA-interacting protein), also known as AURKAIP1 (aurora kinase A interacting protein 1) or AIP, is a 199 amino acid protein that localizes to the nucleus and is ubiquitously expressed, with highest levels present in testis, heart and skeletal muscle. Interacting specifically with ARK-1 (aurora kinase 1), AKIP functions to induce the proteasomal-dependent degradation of ARK-1, thereby acting as a negative regulator of ARK-1 activity. AKIP is encoded by a gene which maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. |
Other Clones
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Other Formats
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Unconjugated
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