B7-1/CD80 Polyclonal Antibody (AN005820L)
For research use only.
| Verified Samples | Verified Samples in IHC: Human tonsil |
| Dilution | IHC 1:100-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant Human B7-1/CD80 protein expressed by Mammalian |
| Abbre | B7-1/CD80 |
| Synonyms | B lymphocyte activation antigen B7, B7-1 antigen, B7-1 antigen, CD28 antigen ligand 1, CD80 antigen, CD80 antigen CD28 antigen ligand 1, CD80 molecule, Costimulatory factor CD80, costimulatory molecule variant IgV-CD80, LAB, CTLA-4 counter-receptor B, T-lymphocyte activation antigen CD, B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7, CD80, CD28LGB7-1 antigen, T-lymphocyte activation antigen CD80, Activation B7-1 antigen, CTLA-4 counter-receptor B7.1, B7-1, BB1 |
| Swissprot | |
| Cellular Localization | Cell membrane |
| Tissue Specificity | Expressed on activated B-cells, macrophages and dendritic cells. |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Immunology, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
| background | B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20‑100 fold higher affinity than CD28 and is involved in the down‑regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. |
Other Clones
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Other Formats
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Unconjugated
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