BAD Polyclonal Antibody (E-AB-13813)
For research use only.
Verified Samples |
Verified Samples in IHC: Human colon cancer, Human esophagus cancer |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human BAD |
Abbre | BAD |
Synonyms | AI325008, BAD, BBC 2, BBC2, BBC6, BCL X / BCL 2 Binding Protein, BCL X Binding Protein, Bcl 2 Antagonist of Cell Death, Bcl 2 Binding Component 6, Bcl XL/Bcl 2 Associated Death Promoter, Bcl-2-binding component 6, Bcl-2-like protein 8, Bcl-XL/Bcl-2-associated dea |
Swissprot | |
Cellular Localization | Mitochondrion outer membrane. Cytoplasm. Upon phosphorylation, locates to the cytoplasm. |
Concentration | 0.4 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer, Cell Biology, Metabolism |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. |
Other Clones
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Other Formats
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Unconjugated
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