BAG3 Polyclonal Antibody (E-AB-65122)

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Size	Price	Qty
200μL	$ 530.00	- +
120μL	$ 320.00	- +
60μL	$ 200.00	- +

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Verified Samples	Verified Samples in IHC: Rat heart, Human lung, Human lung cancer, Human breast cancer, Mouse heart
Dilution	IHC 1:50-1:100
Isotype	IgG
Host	Rabbit
Reactivity	Human, Mouse, Rat
Applications	IHC
Clonality	Polyclonal
Immunogen	Recombinant fusion protein of human BAG3 (NP_004272.2).
Abbre	BAG3
Synonyms	BAG-3, BAG3, BIS, CAIR-1, MFM6
Swissprot	O95817
Cellular Localization	Cytosol, Nucleus, Plasma Membrane, Other locations: cytoplasm, neuron projection, Z disc.
Concentration	1 mg/mL
Buffer	Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method	Affinity purification
Research Areas	Cancer, Cell Biology, Metabolism
Conjugation	Unconjugated
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping	The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background	BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Cat.No.	Product Name	Sizes
E-AB-1003	Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated)	500μL , 120μL , 60μL
E-AB-1043	Streptavidin(peroxidase/HRP conjugated)	500μL , 120μL , 60μL
E-AB-1194	HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed	500μL , 120μL , 1mL
E-IR-R217	2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)	50mL , 18mL , 6mL , 3mL
E-IR-R220	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0)	10mL , 3mL
E-IR-R221	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0)	10mL , 3mL
E-IR-R304A	Western Blot Detection Kit	50Assays
E-IR-R304B	High Accuracy and Absorbability Western Blot Detection Kit	50Assays

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Unconjugated