BAIAP2 Polyclonal Antibody (E-AB-10414)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human colon cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human BAIAP2 |
| Abbre | BAIAP2 |
| Synonyms | BAI-associated protein 2, BAI1 associated protein 2, BAI1-associated protein 2, BAIAP 2, BAIP2, BAP2, Baiap2, Brain-specific angiogenesis inhibitor 1-associated protein 2, FLAF3, Fas ligand-associated factor 3, Insulin receptor substr, Insulin receptor substrate p53 |
| Swissprot | |
| Cellular Localization | Cytoplasm. Membrane. Cell projection>filopodium. Cell projection>ruffle. Detected throughout the cytoplasm in the absence of specific binding partners. Detected in filopodia and close to membrane ruffles. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms |
Other Clones
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Unconjugated
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