BCAS4 Polyclonal Antibody (E-AB-16277)
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For research use only.
| Verified Samples |
Verified Samples in WB: Mouse spleen Verified Samples in IHC: Human gastric cancer, Human thyroid cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human BCAS4 |
| Abbre | BCAS4 |
| Synonyms | BCAS4, BCAS4/BCAS3 fusion, Breast carcinoma amplified sequence 4, Breast carcinoma amplified sequence 4/3 fusion protein, Breast carcinoma-amplified sequence 4, CNOL, FLJ20495, RP5-1071L10.2 |
| Swissprot | |
| Calculated MW | 23 kDa |
| Cellular Localization | Cytoplasm. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The gene encoding BCAS4 (Breast carcinoma-amplified sequence 4), a 211 amino acid protein, is found in a region on chromosome 20 that is frequently amplified in human breast cancer.The amplification and translocation between the BCAS4 gene and the BCAS3 gene, with a 17q23 locus, results in a fusion transcript that is overexpressed in MCF-7 cells.Also, deletion of chromosomal region 20q13.13-q13.2 and resultant deletion of BCAS4, as well as three other genes, is the cause of Okihiro syndrome, a disease characterized by ocular and upper limb anomalies. |
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