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For research use only.

Verified Samples Verified Samples in IHC: Human thyroid cancer, Human brain
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human BGLAP
Abbre BGLAP
Synonyms BGLAP,  BGP,  Bone Gla protein,  Bone gamma carboxyglutamate (gla) protein,  Bone gamma carboxyglutamate gla protein osteocalcin,  Bone gamma carboxyglutamate protein,  Gamma carboxyglutamic acid containing protein,  Gamma-carboxyglutamic acid-containing protein,  OC,  OCN
Swissprot
Cellular Localization Secreted.
Concentration 0.5 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Signal Transduction,  Stem Cells
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Bone gamma-carboxyglutamic acid (Gla) protein, known as BGLAP, BGP or osteocalcin, is an abundant, non-collagenous protein component of bone that is produced by osteoblasts.In mice, osteocalcin is composed of a cluster of 3 genes known as OG1, OG2 and ORG, all of which can be found within a 23Kb span of genomic DNA.Human osteocalcin is a highly conserved, 46-50 amino acid, single chain protein that contains three vitamin K-dependent g-carboxyglutamic acid residues.Osteocalcin appears transiently in embryonic bone at the time of mineral deposition, where it binds to hydroxyapatite in a calcium-dependent manner.
Other Clones

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Unconjugated

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