BID Polyclonal Antibody (E-AB-60014)
For research use only.
| Verified Samples |
Verified Samples in IF: C6, NIH/3T3, U2OS |
| Dilution | IF 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IF |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human BID (NP_001187.1). |
| Abbre | BID |
| Synonyms | BID, FP497 |
| Swissprot | |
| Cellular Localization | Cytoplasm, Cytoplasm, Mitochondrion membrane, When uncleaved, it is predominantly cytoplasmic, Mitochondrion membrane, A significant proportion of isoform 2 localizes to mitochondria, it may be cleaved constitutively, Mitochondrion membrane, Associated with the mitochondrial membrane and Mitochondrion membrane, Translocates to mitochondria as an integral membrane protein. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Metabolism |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. |
Other Clones
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Other Formats
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Unconjugated
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