Biotin Anti-Mouse CD117/c-Kit Antibody[2B8] (E-AB-F1092B)

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	100μg	$ 82.00	- +
	25μg	$ 36.00	- +

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Isotype	Rat IgG2b, κ
Host	Rat
Reactivity	Mouse
Applications	FCM
Clonality	Monoclonal
Abbre	CD117
Synonyms	CD117, Kit, Mast/stem cell growth factor receptor Kit, Proto-oncogene c-Kit, SCFR, Tyrosine-protein kinase Kit, c-Kit
Swissprot	P05532
Cellular Localization	Membrane
Concentration	0.5 mg/mL
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Immunology, Stem Cells
Clone No.	2B8
Conjugation	Biotin
Storage	This product can be stored at 2-8°C for 12 months. Do not freeze.
Shipping	Ice bag
background	CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.