Biotin Anti-Mouse CD209b Antibody[22D1] (E-AB-F1022B)
| Isotype | Armenian Hamster IgG |
| Host | Armenian Hamster |
| Reactivity | Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Isotype Control | Biotin Armenian Hamster IgG Isotype Control[PIP] |
| Abbre | CD209b |
| Synonyms | CD209, CD209 antigen-like protein B, Cd209b, DC-SIGN-related protein 1, DC-SIGNR1, OtB7 |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Clone | 22D1 |
| Conjugation | Biotin |
| Storage | This product can be stored at 2-8°C for 24 months. Do not freeze. |
| Shipping | Ice bag |
| background | CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway. |
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