Biotin Anti-Mouse CD54 Antibody[YN1/1.7.4] (E-AB-F1018B)
For research use only.
| Alternate Names | CD54, Icam-1, Icam1, Intercellular adhesion molecule 1, MALA-2, MyD10 |
| Clone No | |
| Leadtime | Order now, ship in 3 days |
| Background | CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues. |
| Abbre | CD54 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype | Rat IgG2b, κ |
| Isotype Control | E-AB-F09843B |
| Applications |
FCM
|
| Research Areas | Cell Adhesion;Cell Biology;Costimulatory Molecules;Immunology;Innate Immunity;Neuroscience;Neuroscience Cell Markers;Stem Cells |
| Cellular Localization |
Membrane
|
| Form | Liquid |
| Concentration |
0.5 mg/mL
|
| Conjugation | Biotin |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Other Clones
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Other Formats
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APC
Biotin
Elab Fluor®488
Elab Fluor®647
Elab Fluor®700
FITC
None (AF/LE)
PE
PE/Cyanine 5
PE/Cyanine 5.5
PE/Cyanine 7
PE/Elab Fluor®594
PerCP/Cyanine 5.5
Unconjugated
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