Biotin Anti-Mouse CD62L Antibody[MEL-14] (E-AB-F1011B)

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Cell Markers

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	100μg	$ 108.00	- +
	25μg	$ 48.00	- +

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Conjugation: Biotin

Isotype	Rat IgG2a, κ
Host	Rat
Reactivity	Mouse
Applications	FCM
Clonality	Monoclonal
Abbre	CD62L
Synonyms	CD62L, CD62 antigen-like family member L, L-selectin, LAM-1, LECAM1, Lnhr, Ly-22, Ly22, Lymph node homing receptor, Sell
Swissprot	P18337
Cellular Localization	Membrane
Concentration	0.5 mg/mL
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity
Clone No.	MEL-14
Conjugation	Biotin
Storage	This product can be stored at 2-8°C for 12 months. Do not freeze.
Shipping	Ice bag
background	CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naïve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naïve, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.

Cat.No.	Product Name	Sizes
E-CK-A105	10×ACK Lysis Buffer	500mL , 200mL , 100mL
E-CK-A107	Cell Staining Buffer	500mL , 200mL , 100mL

Cat.No.	Product Name	Clone No.