BOD1 Polyclonal Antibody (E-AB-16283)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human cervical cancer, Human thyroid cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human BOD1 |
| Abbre | BOD1 |
| Synonyms | BOD1, Biorientation defective 1, Biorientation defective protein 1, Biorientation of chromosomes in cell division protein 1, FAM44B, Protein FAM44B, biorientation of chromosomes in cell division 1, family with sequence similarity 44, member B |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytoskeleton>centrosome. Chromosome>centromere>kinetochore. Localizes at the centrosomes throughout the cell cycle, only dissociating during cytokinesis. Localizes at the kinetochore from prometaphase until anaphase. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell biology, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Bod1, a protein conserved throughout metazoans that associates with a large macromolecular complex and localizes with kinetochores and spindle poles during mitosis.Bod1-depleted cells form syntelic attachments that can oscillate and generate enough force to separate sister kinetochores, suggesting that microtubule-kinetochore interactions were intact.Releasing Bod1-depleted cells from a monastrol block increases the frequency of syntelic attachments and the number of cells displaying biorientation defects. |
Other Clones
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Other Formats
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Unconjugated
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