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For research use only.

Verified Samples Verified Samples in IHC: Human thyroid cancer, Human gastric cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human BRK1
Synonyms BRICK1,  BRK1,  Brk1-like,  C3ORF10 GENE,  C3orf10 chromosome 3 open reading frame 10,  Chromosome 3 open reading frame 10,  Haematopoietic stem/progenitor cell prote,  SCAR/WAVE actin nucleating complex subunit,  homolog
Swissprot
Cellular Localization Cytoplasm, cytoskeleton.
Concentration 0.2 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Signal transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background HSPC300 (hematopoietic stem cell protein 300) is also known as probable protein BRICK1 or C3orf10 (chromosome 3 open reading frame 10) and is a 75 amino acid protein that is expressed as two isoforms and localizes to both the cytoplasm and the cytoskeleton.HSPC300 is thought to regulate cytoskeletal organization and Actin polymerization.Free HSPC300 exists as homotrimers prior to its incorporation into the WAVE complex.The WAVE complex includes five proteins, one of which is HSPC300, that regulate the ARC (Arp2/3 complex) which is responsible for Actin nucleation and is Rac 1-dependent.Because HSPC300 is a highly conserved subunit of the WAVE complex across many species, it is thought to have the same or similar functions in many different organisms.
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Unconjugated

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