For research use only.
Verified Samples |
Verified Samples in IHC: Human ovarian cancer, Human esophagus cancer |
Dilution | IHC 1:50-1:300 |
Clonality | Polyclonal |
Immunogen | Fusion protein of human C8orf4 |
Abbre | C8orf4 |
Synonyms | C8orf4, CH004, Chromosome 8 open reading frame 4, Human thyroid cancer 1, MGC22806, TC-1, TC1, Thyroid cancer protein 1, Uncharacterized protein C8orf4 |
Swissprot | |
Concentration | 1.26 mg/mL |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cancer, Epigenetics and Nuclear Signaling, Signal transduction, Stem cells |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. |
Other Clones
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Other Formats
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