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For research use only.

Verified Samples Verified Samples in IHC: Human colon cancer, Human liver cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human CA9
Synonyms CA-IX,  CA9,  CAH9,  CAIX,  Carbonate dehydratase IX,  Carbonic anhydrase 9,  Carbonic anhydrase IX,  Carbonic dehydratase,  G250,  MN,  Membrane antigen MN,  P54/58N,  RCC associated protein G250,  RCC-associated antigen G250,  Renal cell carcinoma-associated antigen G250,  pMW1
Swissprot
Cellular Localization Nucleus. Nucleus, nucleolus. Cell membrane. Cell projection, microvillus membrane. Found on the surface microvilli and in the nucleus, particularly in nucleolus.
Concentration 0.2 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation.
Other Clones

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Unconjugated

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