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For research use only.

Verified Samples Verified Samples in IHC: Human liver cancer, Human ovarian cancer
Dilution IHC 1:40-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human CAMK2A
Abbre CAMK2A
Synonyms Alpha CaMKII,  Ca,  Calcium calmodulin dependent protein kinase II,  Calcium/calmodulin dependent protein kinase II alpha B subunit,  Calcium/calmodulin dependent protein kinase type II alpha chain,  Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha
Swissprot
Cellular Localization Cell junction>synapse>presynaptic cell membrane. Cell junction>synapse. Postsynaptic lipid rafts.
Concentration 0.8 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Cancer,  Cardiovascular,  Metabolism,  Neuroscience,  Signal transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily.Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses.This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta.The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning.In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity.Two transcript variants encoding distinct isoforms have been identified for this gene.
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Unconjugated

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