CAMK2A Polyclonal Antibody (E-AB-19660)

For research use only.
Verified Samples |
Verified Samples in IHC: Human liver cancer, Human ovarian cancer |
Dilution | IHC 1:40-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human CAMK2A |
Abbre | CAMK2A |
Synonyms | Alpha CaMKII, Ca, Calcium calmodulin dependent protein kinase II, Calcium/calmodulin dependent protein kinase II alpha B subunit, Calcium/calmodulin dependent protein kinase type II alpha chain, Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha |
Swissprot | |
Cellular Localization | Cell junction>synapse>presynaptic cell membrane. Cell junction>synapse. Postsynaptic lipid rafts. |
Concentration | 0.8 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Antigen affinity purification |
Research Areas | Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily.Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses.This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta.The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning.In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity.Two transcript variants encoding distinct isoforms have been identified for this gene. |
Other Clones
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Other Formats
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Unconjugated
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