CAPNS1 Polyclonal Antibody (E-AB-13959)
For research use only.
| Verified Samples |
Verified Samples in WB: K562, NIH/3T3 Verified Samples in IHC: Human ovarian cancer, Human brain |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human CAPNS1 |
| Abbre | CAPNS1 |
| Synonyms | 30K, Calcium activated neutral proteinase, Calcium activated neutral proteinase small subunit, Calcium dependent protease small subunit, Calcium dependent protease small subunit 1, Calcium-activated neutral proteinase small subunit, Calcium-dependent protease s |
| Swissprot | |
| Calculated MW | 28 kDa |
| Cellular Localization | Cytoplasm. Cell membrane. Translocates to the plasma membrane upon calcium binding. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene. |
Other Clones
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Other Formats
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Unconjugated
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