CAV3 Polyclonal Antibody (E-AB-16229)
For research use only.
| Verified Samples |
Verified Samples in WB: Human muscle Verified Samples in IHC: Human gastric cancer, Human thyroid cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CAV3 |
| Synonyms | CAV3, Caveolin 3, Caveolin-3, LGMD1C, LQT9, M-caveolin, MGC126100, MGC126101, MGC126129, OTTHUMP00000115603, OTTHUMP00000207105, VIP 21, VIP21 |
| Swissprot | |
| Calculated MW | 17 kDa |
| Cellular Localization | Golgi apparatus membrane. Cell membrane. Membrane>caveola. Potential hairpin-like structure in the membrane. Membrane protein of caveolae. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Developmental Biology, Signal Transduction, Tags and Cell Markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites. |
Other Clones
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Other Formats
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Unconjugated
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