CBR1 Polyclonal Antibody (E-AB-14736)
For research use only.
| Verified Samples |
Verified Samples in WB: Mouse liver, Human fetal lung, Hela, Mouse kidney, Human brain malignant glioma, K562 Verified Samples in IHC: Human cervical cancer, Human colon cancer |
| Dilution | WB 1:1000-1:5000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human CBR1 |
| Abbre | CBR1 |
| Synonyms | 15 hydroxyprostaglandin dehydrogenase [NADP+], 15-hydroxyprostaglandin dehydrogenase [NADP+], CBR 1, CBR1, CRN, Carbonyl Reductase 1, Carbonyl reductase [NADPH] 1, NADPH dependent carbonyl reductase 1, NADPH-dependent carbonyl reductase 1, Prostaglandin 9 ket |
| Swissprot | |
| Calculated MW | 30 kDa |
| Cellular Localization | Cytoplasm. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. |
Other Clones
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Other Formats
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Unconjugated
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