CCDC88A Polyclonal Antibody (E-AB-13059)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human cervical cancer, Human colon cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CCDC88A |
| Abbre | CCDC88A |
| Synonyms | AKT iphosphorylation enhancer, APE, Akt phosphorylation enhancer, Ccdc88a, Coiled coil domain containing 88A, Coiled coil domain containing protein 88A, Coiled-coil domain-containing protein 88A, FLJ10392, G alpha interacting vesicle associated protein, G alpha-in |
| Swissprot | |
| Cellular Localization | Membrane. Cell membrane. Cytoplasm>cytosol. Cytoplasmic vesicle. Cell projection>lamellipodium. Localizes to the cell membrane through interaction with phosphoinositides. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Other Clones
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Other Formats
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Unconjugated
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