CD11B Polyclonal Antibody (E-AB-60354)

For research use only.
Verified Samples |
Verified Samples in IF: Rat bone marrow, RAW264.7, THP-1 |
Dilution | IF 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IF |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein of human CD11B (NP_001139280.1). |
Abbre | CD11B |
Synonyms | CD11B, CD11b/ITAM, CR3A, ITGAM, MAC-1, MAC1A, MO1A, SLEB6 |
Swissprot | |
Cellular Localization | Membrane. |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Neuroscience, Signal Transduction, Stem Cells, Tags and Cell Markers |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. |
Other Clones
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Other Formats
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Unconjugated
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