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For research use only.

Verified Samples Verified Samples in IHC: Human lymphoma, Human cervical cancer
Dilution IHC 1:100-1:300
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human PTPRC
Abbre PTPRC
Synonyms B220,  CD 45,  CD45,  CD45 antigen,  CD45R,  GP180,  L-CA,  LCA,  LY5,  Leukocyte common antigen,  Ly-5,  Ly5,  Lyt-4,  OTTHUMP00000033813,  OTTHUMP00000033816,  OTTHUMP00000033817,  OTTHUMP00000038574,  Protein tyros,  Protein tyrosine phosphatase receptor type c polypeptide,  homolog of,  loc
Swissprot
Cellular Localization Membrane
Concentration 0.7 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Immunology,  Neuroscience,  Signal transduction,  Stem cells
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family.PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation.This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP.This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling.It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling.
Other Clones

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Unconjugated

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