CD54 Polyclonal Antibody (E-AB-14711)

For research use only.
Verified Samples |
Verified Samples in WB: Raji, HUVEC Verified Samples in IHC: Human gastric cancer, Human liver cancer |
Dilution | WB 1:1000-1:5000, IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | WB, IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human ICAM1 |
Abbre | ICAM1 |
Synonyms | Antigen identified by monoclonal BB2, BB 2, BB2, CD 54, CD54, CD_antigen=CD54, Cell surface glycoprotein P3.58, Human rhinovirus receptor, ICAM 1, ICAM-1, ICAM1, Intercellular adhesion molecule, human rhinovirus receptor, intercellular adhesion molecule 1 (CD54) |
Swissprot | |
Calculated MW | 58 kDa |
Cellular Localization | Membrane |
Concentration | 0.6 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Immunology, Stem Cells |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
Other Clones
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Other Formats
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Unconjugated
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