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For research use only.

Verified Samples Verified Samples in WB: Raji, HUVEC
Verified Samples in IHC: Human gastric cancer, Human liver cancer
Dilution WB 1:1000-1:5000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human ICAM1
Abbre ICAM1
Synonyms Antigen identified by monoclonal BB2,  BB 2,  BB2,  CD 54,  CD54,  CD_antigen=CD54,  Cell surface glycoprotein P3.58,  Human rhinovirus receptor,  ICAM 1,  ICAM-1,  ICAM1,  Intercellular adhesion molecule,  human rhinovirus receptor,  intercellular adhesion molecule 1 (CD54)
Swissprot
Calculated MW 58 kDa
Cellular Localization Membrane
Concentration 0.6 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Immunology,  Stem Cells
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Other Clones

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Unconjugated

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