CDC27 Polyclonal Antibody (E-AB-16327)
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For research use only.
| Verified Samples |
Verified Samples in WB: HepG2, K562 Verified Samples in IHC: Human lung cancer |
| Dilution | WB 1:500-1:2000, IHC 1:25-1:100 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CDC27 |
| Abbre | CDC27 |
| Synonyms | ANAPC3, Anaphase Promoting Complex 3, Anaphase promoting complex protein 3, Anaphase Promoting Complex Subunit 3, Anaphase-promoting complex subunit 3, APC 3, APC3, Cdc 27, CDC27, CDC27 homolog, CDC27Hs, Cell Division Cycle 27, Cell division cycle protein 27 ho, Cell division cycle protein 27 homolog, D0S1430E, D17S978E, H NUC, H-NUC, HNUC, Nuc2 homolog抗体 |
| Swissprot | |
| Calculated MW | 92 kDa |
| Cellular Localization | Nucleus |
| Concentration | 0.30 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell biology |
| Conjugation | Unconjugated |
| Storage | Store at -20℃ Valid for 12 months. Avoid freeze/thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. |
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