CDC42BPA Polyclonal Antibody (E-AB-17780)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer, Human lung cancer |
| Dilution | IHC 1:40-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CDC42BPA |
| Abbre | CDC42BPA |
| Synonyms | A930014J19Rik, CDC42 binding protein kinase alpha, CDC42 binding protein kinase alpha (DMPK like), CDC42 binding protein kinase alpha dmpk like, CDC42 binding protein kinase beta, CDC42-binding protein kinase alpha, CDC42BPA, DKFZp686L1738, DKFZp686P1738, DMPK lik |
| Swissprot | |
| Cellular Localization | Cytoplasm. Displays a dispersed punctate distribution and concentrates along the cell periphery, especially at the leading edge and cell-cell junction. This concentration is PH-domain dependent. |
| Concentration | 0.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. |
Other Clones
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Other Formats
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Unconjugated
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