CDKN3 Polyclonal Antibody (E-AB-60584)
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For research use only.
| Verified Samples |
Verified Samples in IF: MCF-7 |
| Dilution | IF 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IF |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human CDKN3 (NP_001124323.1). |
| Abbre | CDKN3 |
| Synonyms | CDI1, CDKN3, CIP2, KAP, KAP1 |
| Swissprot | |
| Cellular Localization | Cytoplasm>perinuclear region. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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