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For research use only.

Verified Samples Verified Samples in IHC: Human colon cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human CENPC
Abbre CENPC
Synonyms CENP-C,  CENP-C 1,  CENPC,  CENPC1,  Centromere autoantigen C,  Centromere autoantigen C1,  Centromere protein C,  Centromere protein C 1,  ICEN7,  Interphase centromere complex protein 7,  MIF2,  hcp-4
Swissprot
Cellular Localization Nucleus. Chromosome>centromere>kinetochore. Localizes exclusively in the kinetochore domain of centromeres.
Concentration 0.6 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.
Other Clones

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Unconjugated

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