CENPC Polyclonal Antibody (E-AB-11073)
For research use only.
Verified Samples |
Verified Samples in IHC: Human colon cancer |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human CENPC |
Abbre | CENPC |
Synonyms | CENP-C, CENP-C 1, CENPC, CENPC1, Centromere autoantigen C, Centromere autoantigen C1, Centromere protein C, Centromere protein C 1, ICEN7, Interphase centromere complex protein 7, MIF2, hcp-4 |
Swissprot | |
Cellular Localization | Nucleus. Chromosome>centromere>kinetochore. Localizes exclusively in the kinetochore domain of centromeres. |
Concentration | 0.6 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. |
Other Clones
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Other Formats
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Unconjugated
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