CEP55 Polyclonal Antibody (E-AB-11074)
For research use only.
| Verified Samples |
Verified Samples in WB: Hela |
| Dilution | WB 1:200-1:1000 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human CEP55 |
| Abbre | CEP55 |
| Synonyms | C10orf3, CEP 55, CEP55, CT111, Centrosomal protein 55kDa, Centrosomal protein of 55 kDa, Cep55, FLJ10540, URCC 6, URCC6, Up regulated in colon cancer 6, Up-regulated in colon cancer 6, cancer/testis antigen 111 |
| Swissprot | |
| Calculated MW | 54 kDa |
| Cellular Localization | Cytoplasm>cytoskeleton>centrosome>centriole. Cytoplasm>cytoskeleton>centrosome. Cleavage furrow. Midbody. Present at the centrosomes at interphase. A small portion is associated preferentially with the mother centriole, whereas the majority localizes to the pericentriolar material. During mitosis, loss of affinity for the centrosome at the onset of prophase and diffusion throughout the cell. This dissociation from the centrosome is phosphorylation-dependent. May remain localized at the centrosome during mitosis in certain cell types. Appears at the cleavage furrow in late anaphase and in the midbody in cytokinesis. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Centrosomal protein of 55 kDa is a protein that in humans is encoded by the CEP55 gene.CEP55 is a mitotic phosphoprotein that plays a key role in cytokinesis, the final stage of cell division.Interacts (phosphorylated on Ser-425 and Ser-428) with PLK1.Interacts with AKAP9; the interaction occurs in interphase and is lost upon mitotic entry.Interacts with PCNT; the interaction occurs in interphase and is lost upon mitotic entry.Interacts with PDCD6IP; the interaction is direct; CEP55 binds PDCD6IP in a 2:1 stoechiometry; PDCD6IP competes with TSG101 for the same binding site. |
Other Clones
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Unconjugated
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