CERK Polyclonal Antibody (E-AB-14742)
For research use only.
Verified Samples |
Verified Samples in IHC: Human tonsil, Human thyroid cancer |
Dilution | IHC 1:25-1:100 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human CERK |
Abbre | CERK |
Synonyms | Acylsphingosine kinase, CERK1, Ceramide kinase, Cerk, KIAA1646, LK4, Lipid kinase 4, Lipid kinase LK4, dA59H18.2, dA59H18.3, hCERK |
Swissprot | |
Cellular Localization | Cytoplasm. Membrane. |
Concentration | 0.4 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cell Biology |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation. Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides. |
Other Clones
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Other Formats
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Unconjugated
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