For research use only.
Verified Samples |
Verified Samples in IHC: Human stomach |
Dilution | IHC 1:50-1:200 |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein of human CHIT1 (NP_003456.1). |
Synonyms | CHI3, CHIT, CHIT1, CHITD |
Swissprot | |
Cellular Localization | Secreted. Lysosome. A small proportion is lysosomal. |
Concentration | 1 mg/mL |
Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method | Affinity purification |
Research Areas | Immunology |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. |
Other Clones
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Other Formats
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Unconjugated
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