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CHIT1 Polyclonal Antibody (E-AB-62673)

All Size Price Qty
200μL $ 530.00
120μL $ 320.00
60μL $ 200.00
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For research use only.

Verified Samples Verified Samples in IHC: Human stomach
Dilution IHC 1:50-1:200
Clonality Polyclonal
Immunogen Recombinant fusion protein of human CHIT1 (NP_003456.1).
Synonyms CHI3,  CHIT,  CHIT1,  CHITD
Swissprot
Cellular Localization Secreted. Lysosome. A small proportion is lysosomal.
Concentration 1 mg/mL
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method Affinity purification
Research Areas Immunology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.
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Unconjugated

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