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For research use only.

Verified Samples Verified Samples in IHC: Human thyroid cancer, Human gastric cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human CHMP1A
Abbre CHMP1A
Synonyms CHM1A,  CHMP1a,  Charged multivesicular body protein 1a,  Chromatin modifying protein 1a,  Chromatin-modifying protein 1a,  KIAA0047,  Metalloprotease 1,  PCOLN3,  PRSM1,  Procollagen (type III) N endopeptidase,  Vacuolar prote,  Vacuolar protein sorting 46 1,  hVps46 1,  hVps46-1
Swissprot
Cellular Localization Cytoplasm. Endosome membrane. Nucleus matrix. The cytoplasmic form is partially membrane-associated and localizes to early endosomes. The nuclear form remains associated with the chromosome scaffold during mitosis. On overexpression, it localizes to nuclear bodies characterized by nuclease-resistant condensed chromatin.
Concentration 0.4 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the CHMP/Chmp family of proteins which are involved in multivesicular body sorting of proteins to the interiors of lysosomes. The initial prediction of the protein sequence encoded by this gene suggested that the encoded protein was a metallopeptidase. The nomenclature has been updated recently to reflect the correct biological function of this encoded protein. Several transcripts encoding different isoforms have been found for this gene.
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Unconjugated

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