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For research use only.

Verified Samples Verified Samples in IHC: Human colon cancer, Human lung cancer
Dilution IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human CHRNA10
Abbre CHRNA10
Synonyms ACH10,  Acetylcholine receptor,  Alpha 10 nAChR,  CHRNA 10,  CHRNA10,  Cholinergic receptor,  Cholinergic receptor nicotinic alpha 10,  NACHR,  alpha polypeptide 10,  alpha-10 subunit,  neuronal nicotinic,  nicotinic
Swissprot
Cellular Localization Cell junction>synapse>postsynaptic cell membrane. Cell membrane.
Concentration 0.5 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Neuroscience,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.
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Unconjugated

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