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For research use only.

Verified Samples Verified Samples in IHC: Human brain
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human CHRNA4
Abbre CHRNA4
Synonyms A4 nicotinic receptor,  ACH 4,  ACH4,  ACHA4,  AChR,  Acetylcholine receptor alpha 4 neural,  Acetylcholine receptor neuronal nicotinic alpha 4 subunit,  Acra 4,  Acra4,  Alpha4 nAChR,  BFNC,  Cholinergic receptor nicotinic alpha 4,  Cholinergic receptor nicotinic alpha polypept
Swissprot
Cellular Localization Cell junction>synapse>postsynaptic cell membrane. Cell membrane.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Metabolism,  Neuroscience
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses.These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane.This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor.Mutations in this gene cause nocturnal frontal lobe epilepsy type 1.
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Unconjugated

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