CIDEA Polyclonal Antibody (E-AB-62677)
For research use only.
Verified Samples |
Verified Samples in IF: A549 |
Dilution | IF 1:50-1:100 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | IF |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein of human CIDEA (NP_001270.1). |
Abbre | CIDEA |
Synonyms | CIDE-A, CIDEA |
Swissprot | |
Cellular Localization | Nuclear, Cytoplasm, mitochondrial envelope, lipid droplet. |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. |
Other Clones
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Other Formats
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Unconjugated
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