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For research use only.

Verified Samples Verified Samples in IF: A549
Dilution IF 1:50-1:100
Isotype IgG
Host Rabbit
Reactivity Human
Applications IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human CIDEA (NP_001270.1).
Abbre CIDEA
Synonyms CIDE-A,  CIDEA
Swissprot
Cellular Localization Nuclear, Cytoplasm, mitochondrial envelope, lipid droplet.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Cardiovascular,  Epigenetics and Nuclear Signaling,  Metabolism
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
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Unconjugated

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