CK-6A/B/C Polyclonal Antibody (E-AB-15555)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human breast cancer, Human ovarian cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human KRT6A/KRT6B/KRT6C |
| Abbre | KRT6A/KRT6B/KRT6C |
| Synonyms | CK-6B, CK6A, CK6B, CK6C, CK6D, K6A, K6B, K6C, K6D, K6E, KRT6C, KRT6D, KRT6E, KRTL1, PC2 |
| Swissprot | |
| Cellular Localization | Cytoskeleton, intermediate filament, keratin filament, Cytosol, Extracellular region or secreted, extracellular exosome. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction, Tags and Cell Markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. |
Other Clones
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Other Formats
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Unconjugated
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