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For research use only.

Verified Samples Verified Samples in WB: Hela
Verified Samples in IHC: Human liver cancer, Human ovarian cancer
Dilution WB 1:2000-1:5000,  IHC 1:100-1:300
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human CLDN1
Abbre CLDN1
Synonyms CLD 1,  CLD1,  CLDN 1,  Claudin-1,  Claudin1,  Cldn1,  ILVASC,  SEMP 1,  SEMP1,  Senescence associated epithelial membrane protein,  Senescence associated epithelial membrane protein 1,  Senescence-associated epithelial membrane protein
Swissprot
Calculated MW 23 kDa
Cellular Localization Cell junction, tight junction. Cell membrane.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
Other Clones

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Unconjugated

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